1,371 research outputs found

    The motion of superconducting vortices in thin films of varying thickness

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    The interaction of superconducting vortices with superconductor/vacuum interfaces is considered. A vortex is first shown to intersect such an interface normally. Various thin-film models are then formulated, corresponding to different parameter regimes. A local analysis of a vortex is performed, and a law of motion for each vortex deduced. This law of motion implies that the vortex will move to the locally thinnest part of the film, and is consistent with the vortex moving under the curvature induced by being forced to intersect the boundaries of the film normall

    The timing of maternal depressive symptoms and child cognitive development: a longitudinal study.

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    Background: Maternal depression is known to be associated with impairments in child cognitive development, although the effect of timing of exposure to maternal depression is unclear. Methods: Data collected for the Avon Longitudinal Study of Parents and Children, a longitudinal study beginning in pregnancy, included self-report measures of maternal depression the Edinburgh Postnatal Depression Scale, completed on 6 occasions up to 3 years of age, and IQ of the index child (WISC) measured at aged 8 years. We used these data to assign women to 8 groups according to whether depression occurred in the antenatal, postnatal, preschool period, any combination of these times, or not at all. We compared a model comprising all patterns of depression (saturated model) with models nested within this to test whether there is a relationship between depression and child cognitive development and, if so, whether there is a sensitive period. We then investigated the relationship with child IQ for each model, following adjustment for confounders. Results: Six thousand seven hundred and thirty-five of 13,615 children from singleton births (49.5%, of eligible core sample) attended a research clinic at 8 years and completed a WISC with a score ≥ 70. A total of 5,029 mothers of these children had completed mood assessments over the 3 time periods. In unadjusted analyses, all three sensitive period models were as good as the saturated model, as was an accumulation model. Of the sensitive period models, only that for antenatal exposure was a consistently better fit than the accumulation model. After multiple imputation for missing data (to n = 6,735), there was no effect of postnatal depression on child IQ independent of depression at other times [-0.19 IQ points, 95% confidence interval (CI) -1.5 to 1.1 points]. There was an effect of antenatal depression (-3.19 IQ points, 95% CI: -4.33 to -2.06) which attenuated following adjustment (-0.64 IQ points, 95% CI: -1.68 to 0.40). Conclusions: The postnatal period is not a sensitive one for the effect of maternal depression on child cognitive development. © 2011 The Authors. Journal of Child Psychology and Psychiatry

    Finite Temperature Phase Diagram of Quasi-Two-Dimensional Imbalanced Fermi Gases Beyond Mean-Field

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    We investigate the superfluid transition temperature of quasi-two-dimensional imbalanced Fermi gases beyond the mean-field approximation, through the second-order (or induced) interaction effects. For a balanced Fermi system the transition temperature is suppressed by a factor 2.72\approx 2.72. For imbalanced Fermi systems, the polarization and transition temperature of the tricritical point are significantly reduced as the two-body binding energy ϵB|\epsilon_B| increases.Comment: 6 pages, 3 figure

    A boarding school outbreak of pertussis in adolescents : value of laboratory diagnostic methods

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    Culture for Bordetella pertussis (B. pertussis) is the traditional gold standard for laboratory diagnosis of pertussis but is insensitive, especially later in the course of illness and in vaccinated persons. Interpretation of serology is limited by the lack of an appropriate reference standard. An outbreak of pertussis in a crowded boarding-school dormitory allowed evaluation of laboratory correlates of infection. Questionnaires, serum samples and throat swabs were collected from members of the exposed group. Serum samples from unexposed controls of a similar age group were used for comparison. B. pertussis PCR was performed on throat swabs, and sera were tested for IgA antibodies against whole-cell (WC) B. pertussis antigen and IgG antibodies to pertussis toxin (PT). The Centers for Disease Control and Prevention definition for pertussis was used to define clinical cases. We evaluated the use of a previously published cut-off for PT IgG of 125 EIA units (EU)/ml. Completed questionnaires were obtained from 115 students, of whom 85 (74%) reported coughing symptoms, including 32 (28%) who met the clinical case definition for pertussis. B. pertussis was detected by PCR in 17 (15%) and WC IgA in 22 (19%) students; neither correlated with symptoms, but dormitory of residence strongly predicted PCR status. The mean PT IgG geometric mean concentration, in this situation of high pertussis exposure, correlated with severity of symptoms and was significantly higher in both symptomatic and asymptomatic children exposed during the outbreak (P&lt;0&middot;001) than in control children. A cut-off for PT IgG of 125 EU/ml was too high in an outbreak situation to be sensitive enough to identify pertussis cases. A case of pertussis in a crowded boarding-school dormitory resulted rapidly in an outbreak. Serology and PCR were useful in identifying the outbreak and commencing disease control measures. The use of serology has mostly been evaluated in community serosurveys, where it is not possible to determine if immunity reflects vaccination, asymptomatic disease or symptomatic disease. This outbreak gave us the opportunity to evaluate the value of serology and PCR in the presence of confirmed exposure to pertussis.<br /

    An All-Cryogenic THz Transmission Spectrometer

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    This paper describes a THz transmission spectrometer for the spectral range of 2-65 cm^-1 (100 GHz to 2 THz) with a spectral resolution of at least 1.8 cm^-1 (50 GHz) where the source, sample, and detector are all fully contained in a cryogenic environment. Cyclotron emission from a two-dimensional electron gas heated with an electrical current serves as a magnetic field tunable source. The spectrometer is demonstrated at 4.2 K by measuring the resonant cyclotron absorption of a second two dimensional electron gas. Unique aspects of the spectrometer are that 1) an ultra-broadband detector is used and 2) the emitter is run quasi-continuously with a chopping frequency of only 1 Hz. Since optical coupling to room temperature components is not necessary, this technique is compatible with ultra-low temperature (sub 100 mK) operation.Comment: 7 pages, 5 figures. Author affiliation and funding acknowledgements clarifie

    New Perspectives on Glacial Geomorphology in Earth's Deep Time Record

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    International audienceThe deep time (pre-Quaternary) glacial record is an important means to understand the growth, development, and recession of the global cryosphere on very long timescales (10 6-10 8 Myr). Sedimentological description and interpretation of outcrops has traditionally played an important role. Whilst such data remain vital, new insights are now possible thanks to freely accessible aerial and satellite imagery, the widespread availability and affordability of Uncrewed Aerial Vehicles, and accessibility to 3D rendering software. In this paper, we showcase examples of glaciated landscapes from the Cryogenian, Ediacaran, Late Ordovician and Late Carboniferous where this approach is revolutionizing our understanding of deep time glaciation. Although some problems cannot be overcome (erosion or dissolution of the evidence), robust interpretations in terms of the evolving subglacial environment can be made. Citing examples from Australia (Cryogenian), China (Ediacaran), North and South Africa (Late Ordovician, Late Carboniferous), and Namibia (Late Carboniferous), we illustrate how the power of glacial geomorphology can be harnessed to interpret Earth's ancient glacial record
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